Check our new paper in ACS Nano Journal about amplification-free mitochondrial DNA quantification
In our latest research, we introduce a solid-state nanopore method for label-free, amplification-free detection of mitochondrial DNA (mtDNA), a key biomarker for disease. Using machine learning and exonuclease digestion, we achieve high accuracy in distinguishing mtDNA from genomic DNA in biological samples. This approach offers picomolar sensitivity with minimal preparation, making it ideal for clinical diagnostics.
Noam presented his final PhD seminar entitled "Single-Molecule Protein Sensing for Early AMD Diagnosis”
In his seminar, he talked about the use of single-molecule sensing technology for early detection of age-related macular degeneration (AMD), a leading cause of vision loss in older adults. Unlike traditional methods that detect physical damage, this approach analyzes molecular biomarkers like VEGF and Clusterin with high precision. Single-molecule techniques, such as nanopore-based sensors or dynamic sensing using nanoparticles, allow real-time tracking of individual protein interactions, enabling ultrasensitive detection at subfemtomolar levels. These methods improve diagnostic accuracy by identifying molecular changes before significant vision loss occurs, paving the way for earlier intervention and personalized treatments. This innovation could transform AMD management, reducing its socioeconomic impact and enhancing patient outcomes.
Success at SMPS 2025 Conference in Bolzano, Italy
Part of our lab team: Prof. Meller, Dr. Marzia Issorai, Dr. Navneet Varma, and Zoahr Rosentock participated in the SMPS 2025 Conference in Bolzano, Italy.
The SMPS 2025 Conference brings together leading experts in Soft Matter and Polymers, offering a platform for groundbreaking research and collaboration. Prof. Meller was a featured speaker, giving a lecture on our lab's SMPS research.
Congratulations to Dr. Marzia on winning the First Poster Prize. This remarkable achievement highlights our lab's innovative research.
You can learn more about the conference here.
Welcome to Meller lab, Ali Kayyal!
Ali Kayyal, new MSc student joined our Lab.
Ali’s research will focus on developing an innovative deep-learning approach for protein classification, using data derived from protein sensing and tracking experiments. This work aims to improve classification accuracy and reveal subtle patterns within protein structures and dynamics, advancing proteomic analysis.
Welcome to our team Ali and best of luck!
Celebrating Rosh Hashanah in Meller lab
As we welcome the Jewish New Year, Rosh Hashanah, our lab takes a moment to reflect on the past year and embrace the opportunities ahead.
We raised a toast to celebrate the new year together.
we wish you a sweet and fulfilling new year! Shana Tova!
Prof. Meller delivers the Inaugural Speech at FARC 2024 conference in IIT Mandi, India.
Professor Meller recently attended the FARC 2024 conference (International Conference on Fundamental and Advanced Research in Chemistry) held at the Indian Institute of Technology Mandi, H.P., India. At this esteemed event, Prof. Meller was honored with the inaugural speech, marking a significant recognition of his groundbreaking contributions to the field of chemistry.
The FARC 2024 conference gathered leading researchers, scholars, and industry experts from around the globe to discuss the latest advancements and innovations in chemistry.
for more information about the FARC 2024 conference click here.
