Meller lab team new paper in Advanced Materials journal
Full-Length Single Protein Molecules Tracking and Counting in thin Silicon Channels
In this paper, we introduce a single-molecule method for parallel protein separation and tracking, yielding multi-dimensional and are electrophoretically separated by their mass/charge in custom-designed thin silicon channel with subwavelength height. This approach allows us to analyse thousands of individual proteins within a few minutes by tracking their motion during the migration. We demonstrate the power of the method by quantifying a cytokine panel for host-response discrimination between viral and bacterial infections.
Check out the recent highlight of Our Nano letters paper featured in Advance in Engineering
Surfing the Nano Wave: Dramatic Leap in DNA Sensing with Surfactant-Coated Nanopores
The online platform of Advances in Engineering has showcased our recent Nano Letters article, titled "Over 30-Fold Enhancement in DNA Translocation Dynamics through Nanoscale Pores Coated with an Anionic Surfactant''.
Read the highlight here
Read the paper here
Neeraj Soni talk at Indian Institute of Technology Mandi
Neeraj Soni, PhD student in Meller lab visited IIT Mandi and presented his PhD work , in which he talked about the feasibility of whole protein identification and sequencing through sub 5nm solid state nanopore.
Neeraj extensively discussed the biophysical characteristics associated with the single-file translocation of whole proteins, underscoring its importance in contrast to traditional methods. Additionally, he delved into inventive strategies for regulating the dynamics of the translocating molecule as it passes through nanopores.
Welcoming our new PhD student Rohan Lamba
Today we welcomed Rohan Lamba to our lab. Rohan Lamba is a new PhD student in our lab. he completed his MSc degree in Chemistry from Indian Institute of Technology (IIT) Mandi. He will be joining our Nanopore team.
We keep on smiling, hoping for great new year 2024.
Happy Holidays from the Meller lab family to Yours.
Dr. Yulia Marom and Dr. Navneet C. Verma from our lab. present the fabrication process of our sensor that can detect single biological molecules - in a 'Holidays' edition.
The tiny sensor (only 4x4 mm), is made of a thin silicon piece that is coated with photoresist (the red material in the video), and the special pattern is exposed to UV light by digital lithography.
The development of the sensor is a significant breakthrough in the early diagnosis of diseases, allowing early treatment and saving lives.
A visit from Sonia and Gerry Rowan, from Toronto, Canada
We had an interesting visit from the Rawan’s, long-time Technion donors.
Sonia and Gerry visited our lab and took part in a translocation experiment of DNA with our AMD team.
At the end of the visit, they received a small souvenir to remember us by.
Thank you very much for your contribution to the advancement of science and specifically to the Technion.
