Prof. Meller won The Diane Sherman Prize for Medical Innovation for a Better World
Prof. Meller was awarded the 2021-2022 Academic Excellence Award :
The Diane Sherman Prize for Medical Innovation for a Better World.
Our paper on SARS-CoV-2 sensing is out in Nanoscale journal.
In our research, we introduced solid-state nanopore sensing using a compact microfluidic device for label-free quantification of SARS-CoV-2 RNA in clinical nasal swab samples. This research was conducted in Prof. Meller’s lab in collaboration with Dr. Ronit Almog and her staff in the epidemiology unit in the Rambam Medical center. We graded nasal swab samples from >15 subjects and found that the SARS-CoV-2 radiometric nanopore index correlates well with the reported RT-qPCR threshold cycle for positive classified samples. Remarkably, nanopore analysis also reports quantitative positive outcomes for clinical samples classified as negative by RT-qPCR, suggesting that the method may be used to diagnose COVID-19 in samples that may evade detection.
Neeraj Soni won the best presentation award at Single Molecule Biophysics Conference, France 2022
Neeraj Soni, a Ph.D. student in our group, won the best presentation award at Single Molecule Biophysics Conference, France 2022.
His presentation title : "Denatured protein translocations using sub 5 nm Solid-state nanopores”.
Proteins are the main constituents of all biological cells and are responsible for most of the cellular functions. Many of the current disease-specific biomarkers are proteins or modified versions of proteins hence creating a need for sensitive yet simple methods for protein identifications in clinical diagnostics applications. Herein, we developed a highly sensitive approach for identifying wide range lengths SDS denatured protein complexes. Given the simplicity and eradication of the tailor-made necessities, this assay holds the full potential to sequence the protein at a single-molecule level in the future.
Way to go Neeraj!
Karawan Halabi broke Israeli record!
Karawan Halabi an MSc student and running athlete from our lab broke the Israeli record of 1000m setting a new one of 2:43.99 minutes after 25 years!
Less than a week before she won the Israeli championship of 5km road race in 16:19 minutes.
Way to go Karawan, keep braking records in sports and engineering.
Liran Taib won the Sherman Excellence Scholarship!
Liran Taib, an MSc student in our lab, won the Sherman Excellence Scholarship for the current academic year.
Liran’s MSc research is Liquid Biopsy Proteins Classification Using Nanochannels Chip for Liver Disease Monitoring.
Congratulations Liran!
Congratulation to Shilo Ohayon!
Shilo Ohayon, a Ph.D. student in our group, won the best poster presentation at the NanoIL 2021.
His poster title : "On-chip protein separation with single-molecule resolution using SDS-PAGE nanochannels”.
The research's main aim is to identify and quantify proteins at a single molecule level using nanochannels. The use of nanochannel allows real-time tracking of the translocating proteins by a computer vision algorithm. The data obtained from each protein enables the identification of the protein and, by that, the whole sample. In the future, this technology could manifest faster and more efficient identification of proteins in biological and clinical samples and eventually will help in more accurate diagnostics.