Nasab Halabi Nasab Halabi

Nitza Burck paper in Clinical Chemistry

Nanopore identification of single nucleotide mutations in circulating tumor DNA by multiplexed ligation:

In this paper we introduce a new and transformative technology, based on sophisticated solid state electro-optical Nanopore biosensors, to enable a highly practical method for DNA mutation identification and quantification.

This proof of principle study demonstrates how coupling our technology together with Ligation based SNV detection could potentially be used for clinical diagnosis of cancer biomarkers, especially relevant for early diagnosis of the disease. By permitting high degree of multiplexing of single nucleotide mutation samples and extremely high accuracy, our approach could offer a rapid and low-cost technique for ctDNA analysis that completely circumvents PCR amplification and library preparation.

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Meller Group Technion Amit Meller Meller Group Technion Amit Meller

Tal Gilboa wins 'Best Poster Presentation' in Nano.IL.2018 conference

The Nano.IL conference is the premier international annual meeting in Nanosciences and Nanotechnology in Israel. On October 11, 2018, our Ph.D. student, Tal Gilboa, won “Best Poster Presentation”, among hundreds of participants. In the poster, she presented her work on Single Molecule Electro-optical Sensing in Solid-state Nanopores.

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